Increased amplitude of low frequency fluctuations but normal hippocampal-default mode network connectivity in schizophrenia

Increased amplitude of low frequency fluctuations but normal hippocampal-default mode network connectivity in schizophrenia

Background: Clinical and preclinical studies have established that the hippocampus is hyperactive in schizophrenia, making it a possible biomarker for drug development. Increased hippocampal connectivity, which can be studied conveniently with resting state imaging, has been proposed as a readily ac...

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Bibliographic Details
Main Authors: Maureen eMcHugo, Baxter P Rogers, Pratik eTalati, Neil D Woodward, Stephan eHeckers
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Psychiatry
Subjects:
Hippocampus
Neuroimaging
Schizophrenia
connectivity
fMRI
biomarkers
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2015.00092/full

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