Role of Flavonoids in the Prevention of AhR-Dependent Resistance During Treatment with BRAF Inhibitors

Role of Flavonoids in the Prevention of AhR-Dependent Resistance During Treatment with BRAF Inhibitors

<b>:</b><b> </b>BRAF and MEK inhibitors (BRAFi and MEKi) are the standard of care for the treatment of metastatic melanoma in patients with BRAF<sup>V600E</sup> mutations, greatly improving progression-free survival. However, the acquisition of resistance to BRAFi...

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Bibliographic Details
Main Authors: Héloïse M. Leclair, Nina Tardif, Anaïs Paris, Marie-Dominique Galibert, Sébastien Corre
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
melanoma
BRAF inhibitor
resistance
AhR
flavonoids
Online Access:https://www.mdpi.com/1422-0067/21/14/5025

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