Hybrid Freeze-Dried Dressings Composed of Epidermal Growth Factor and Recombinant Human-Like Collagen Enhance Cutaneous Wound Healing in Rats

Hybrid Freeze-Dried Dressings Composed of Epidermal Growth Factor and Recombinant Human-Like Collagen Enhance Cutaneous Wound Healing in Rats

Epidermal growth factor (EGF) is important for promoting skin repair and remodeling. Native collagen is also widely used as a scaffold for skin tissue engineering. The limitations of EGF include easy decomposition or inactivation, whereas native collagen is immunogenic and has poor solubility. There...

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Bibliographic Details
Main Authors: Yating Cheng, Yangfan Li, Shiyi Huang, Fenglin Yu, Yu Bei, Yifan Zhang, Jianzhong Tang, Yadong Huang, Qi Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
full-thickness skin defects
cell proliferation
angiogenesis
freeze-dried dressing
recombinant human-like collagen
epidermal growth factor
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00742/full

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