Protein molecular function prediction by Bayesian phylogenomics.

Protein molecular function prediction by Bayesian phylogenomics.

We present a statistical graphical model to infer specific molecular function for unannotated protein sequences using homology. Based on phylogenomic principles, SIFTER (Statistical Inference of Function Through Evolutionary Relationships) accurately predicts molecular function for members of a prot...

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Bibliographic Details
Main Authors: Barbara E Engelhardt, Michael I Jordan, Kathryn E Muratore, Steven E Brenner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1246806?pdf=render

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