Anti-Inflammatory Activity of a Cyclic Tetrapeptide in Mouse and Human Experimental Models

Anti-Inflammatory Activity of a Cyclic Tetrapeptide in Mouse and Human Experimental Models

A cyclic tetrapeptide Pro-Pro-Pheβ<sup>3</sup>ho-Phe (4B8M) was tested for immunosuppressive activity and potential therapeutic utility in several in vitro and in vivo mouse and human models. The tetrapeptide was less toxic for mouse splenocytes in comparison to cyclosporine A (CsA) and...

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Bibliographic Details
Main Authors:	Michał Zimecki, Jolanta Artym, Wojciech Kałas, Leon Strządała, Katarzyna Kaleta-Kuratewicz, Jan Kuryszko, Andrzej Kaszuba, Krzysztof Kaczmarek, Janusz Zabrocki
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Series:	Pharmaceutics
Subjects:	cyclic tetrapeptide tacrolimus pimecrolimus oxazolone toluene diisocyanate colitis
Online Access:	https://www.mdpi.com/1999-4923/12/11/1030

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