Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines

Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines

Facile and biocompatible synthesis of reduced graphene oxide from graphene oxide as a precursor and aqueous leaves extract of Euphorbia heterophylla (L.), act as a reducing /capping /stabilizing agent by green chemistry approaches. The obtained product was analyzed by Ultraviolet-Visible spectroscop...

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Main Authors: K. Lingaraju, H. Raja Naika, G. Nagaraju, H. Nagabhushana
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biotechnology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X19301225
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spelling doaj-bccc6506ce4741a58a2734042c507efa2020-11-24T21:23:15ZengElsevierBiotechnology Reports2215-017X2019-12-0124Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell linesK. Lingaraju0H. Raja Naika1G. Nagaraju2H. Nagabhushana3Department of Studies and Research in Biotechnology, Tumkur University, Tumakuru, 572103, IndiaDepartment of Studies and Research in Biotechnology, Tumkur University, Tumakuru, 572103, India; Corresponding author.Department of Chemistry, Siddaganga Institute of Technology, Tumkur University, Tumakuru, 572103, IndiaProf. C.N.R. Rao Centre for Advanced Material Science, Tumkur University, Tumakuru, 572103, IndiaFacile and biocompatible synthesis of reduced graphene oxide from graphene oxide as a precursor and aqueous leaves extract of Euphorbia heterophylla (L.), act as a reducing /capping /stabilizing agent by green chemistry approaches. The obtained product was analyzed by Ultraviolet-Visible spectroscopy (UV–vis), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy and Scanning electron Microscopy (SEM). In addition to this, the significant cytotoxicity of rGO studied against cancerous cell lines such as A549- Human Lung cancer cell line and HepG2-Human Hepatocarcinoma Cell lines in-vitro. These results indicate that the biocompatible synthesis of rGO is straightforward, inexpensive and environmentally friendly for promising large-scale production of industrial purpose and then finding further biomedical applications. Keywords: Euphorbia heterophylla (L.), Reduced graphene oxide (rGO), X-ray diffraction, Cytotoxicityhttp://www.sciencedirect.com/science/article/pii/S2215017X19301225
collection DOAJ
language English
format Article
sources DOAJ
author K. Lingaraju
H. Raja Naika
G. Nagaraju
H. Nagabhushana
spellingShingle K. Lingaraju
H. Raja Naika
G. Nagaraju
H. Nagabhushana
Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines
Biotechnology Reports
author_facet K. Lingaraju
H. Raja Naika
G. Nagaraju
H. Nagabhushana
author_sort K. Lingaraju
title Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines
title_short Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines
title_full Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines
title_fullStr Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines
title_full_unstemmed Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines
title_sort biocompatible synthesis of reduced graphene oxide from euphorbia heterophylla (l.) and their in-vitro cytotoxicity against human cancer cell lines
publisher Elsevier
series Biotechnology Reports
issn 2215-017X
publishDate 2019-12-01
description Facile and biocompatible synthesis of reduced graphene oxide from graphene oxide as a precursor and aqueous leaves extract of Euphorbia heterophylla (L.), act as a reducing /capping /stabilizing agent by green chemistry approaches. The obtained product was analyzed by Ultraviolet-Visible spectroscopy (UV–vis), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy and Scanning electron Microscopy (SEM). In addition to this, the significant cytotoxicity of rGO studied against cancerous cell lines such as A549- Human Lung cancer cell line and HepG2-Human Hepatocarcinoma Cell lines in-vitro. These results indicate that the biocompatible synthesis of rGO is straightforward, inexpensive and environmentally friendly for promising large-scale production of industrial purpose and then finding further biomedical applications. Keywords: Euphorbia heterophylla (L.), Reduced graphene oxide (rGO), X-ray diffraction, Cytotoxicity
url http://www.sciencedirect.com/science/article/pii/S2215017X19301225
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