HIV-1 Capsid Assembly Inhibitor (CAI) Peptide: Structural Preferences and Delivery into Human Embryonic Lung Cells and Lymphocytes

<p>The Human immunodeficiency 1 derived capsid assembly inhibitor peptide (HIV-1 CAI-peptide) is a promising lead candidate for anti-HIV drug development. Its drawback, however, is that it cannot permeate cells directly. Here we report the transport of the pharmacologically active CAI-peptide...

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Bibliographic Details
Main Author: Klaus Braun, Martin Frank, R&#252;diger Pipkorn, Jennifer Reed, Herbert Spring, J&#252;rgen Debus, Bernd Didinger, Claus-Wilhelm von der Lieth, Manfred Wiessler, Waldemar Waldeck
Format: Article
Language:English
Published: Ivyspring International Publisher 2008-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v05p0230.htm