Notch Signalling in the Hippocampus of Patients With Motor Neuron Disease

Notch Signalling in the Hippocampus of Patients With Motor Neuron Disease

IntroductionThe Notch signalling pathway regulates neuronal survival. It has some similarities with the APP signalling pathway, and competes with the latter for α- and γ-secretase proteolytic complexes. The objective of this study was to study the Notch signalling pathway in the hippocampi of patien...

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Bibliographic Details
Main Authors: Ulises Gómez-Pinedo, Lucía Galán, Jordi A. Matías-Guiu, Vanesa Pytel, Teresa Moreno, Antonio Guerrero-Sola, Jorge Matías-Guiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neuroscience
Subjects:
ALS
Notch
NICD
APP
ADAM10
ADAM17
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00302/full

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