Fibroblast Activation Protein Expressing Mesenchymal Cells Promote Glioblastoma Angiogenesis

Fibroblast Activation Protein Expressing Mesenchymal Cells Promote Glioblastoma Angiogenesis

Fibroblast activation protein (FAP) is a membrane-bound protease that is upregulated in a wide range of tumours and viewed as a marker of tumour-promoting stroma. Previously, we demonstrated increased FAP expression in glioblastomas and described its localisation in cancer and stromal cells. In this...

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Bibliographic Details
Main Authors: Eva Balaziova, Petr Vymola, Petr Hrabal, Rosana Mateu, Michal Zubal, Robert Tomas, David Netuka, Filip Kramar, Zuzana Zemanova, Karla Svobodova, Marek Brabec, Aleksi Sedo, Petr Busek
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
glioblastoma
angiogenesis
microenvironment
fibroblast activation protein
seprase
angiopoietin
Online Access:https://www.mdpi.com/2072-6694/13/13/3304

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