The Botulinum Treatment of Neurogenic Detrusor Overactivity: The Double-Face of the Neurotoxin

The Botulinum Treatment of Neurogenic Detrusor Overactivity: The Double-Face of the Neurotoxin

Botulinum neurotoxin (BoNT) can counteract the highly frequent involuntary muscle contractions and the uncontrolled micturition events that characterize the neurogenic detrusor overactivity (NDO) due to supra-sacral spinal cord lesions. The ability of the toxin to block the neurotransmitter vesicula...

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Bibliographic Details
Main Authors:	Chiara Traini, Maria Giuliana Vannucchi
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Toxins
Subjects:	urinary bladder spinal cord lesion upper lamina propria detrusor urothelium innervation sensory systems afferent nerve endings nerve sprouting
Online Access:	https://www.mdpi.com/2072-6651/11/11/614

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