Hypoxia-induced complement dysregulation is associated with microvascular impairments in mouse tracheal transplants

Hypoxia-induced complement dysregulation is associated with microvascular impairments in mouse tracheal transplants

Abstract Background Complement Regulatory Proteins (CRPs), especially CD55 primarily negate complement factor 3-mediated injuries and maintain tissue homeostasis during complement cascade activation. Complement activation and regulation during alloimmune inflammation contribute to allograft injury a...

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Bibliographic Details
Main Authors: Mohammad Afzal Khan, Talal Shamma, Shadab Kazmi, Abdullah Altuhami, Hala Abdalrahman Ahmed, Abdullah Mohammed Assiri, Dieter Clemens Broering
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Translational Medicine
Subjects:
Complement regulatory proteins
C3d
Acute rejection
Microvascular loss
Online Access:http://link.springer.com/article/10.1186/s12967-020-02305-z

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http://link.springer.com/article/10.1186/s12967-020-02305-z

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