Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space

Immunodominant T cell epitopes preferentially targeted in multiple individuals are the critical element of successful vaccines and targeted immunotherapies. However, the underlying principles of this “convergence” of adaptive immunity among different individuals remain poorly understood. To quantita...

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Bibliographic Details
Main Authors: Masato Ogishi, Hiroshi Yotsuyanagi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00827/full