Treatment of glioblastoma with herbal medicines

• Main Authors: Ivo Trogrlić, Dragan Trogrlić, Darko Trogrlić, Amina Kadrić Trogrlić
• Format: Article
• Language: English
• Published: BMC 2018-02-01
• Series: World Journal of Surgical Oncology
• Subjects: Phytotherapy; Glioblastoma; Recurrence; Nuclear magnetic resonance; Computed tomography
• Online Access: http://link.springer.com/article/10.1186/s12957-018-1329-2

Abstract Background In the latest years, a lot of research studies regarding the usage of active agents from plants in the treatment of tumors have been published, but there is no data about successful usage of herbal remedies in the treatment of glioblastoma in humans. Methods The phytotherapy involved five types of herbal medicine which the subjects took in the form of tea, each type once a day at regular intervals. Three patients took herbal medicine along with standard oncological treatment, while two patients applied for phytotherapy after completing medical treatment. The composition of herbal medicine was modified when necessary, which depended on the results of the control scans using the nuclear magnetic resonance technique and/or computed tomography. Results Forty-eight months after the introduction of phytotherapy, there were no clinical or radiological signs of the disease, in three patients; in one patient, the tumor was reduced and his condition was stable, and one patient lived for 48 months in spite of a large primary tumor and a massive recurrence, which developed after the treatment had been completed. Conclusions The results achieved in patients in whom tumor regression occurred exclusively through the use of phytotherapy deserve special attention. In order to treat glioblastoma more effectively, it is necessary to develop innovative therapeutic strategies and medicines that should not be limited only to the field of conventional medicine. The results presented in this research paper are encouraging and serve as a good basis for further research on the possibilities of phytotherapy in the treatment of glioblastoma.