Significant association between ERCC2 and MTHR polymorphisms and breast cancer susceptibility in Moroccan population: genotype and haplotype analysis in a case-control study

Significant association between ERCC2 and MTHR polymorphisms and breast cancer susceptibility in Moroccan population: genotype and haplotype analysis in a case-control study

Abstract Background Genetic determinants of breast cancer (BC) remained largely unknown in the majority of Moroccan patients. The purpose of this study was to explore the association of ERCC2 and MTHFR polymorphisms with genetic susceptibility to breast cancer in Moroccan population. Methods We geno...

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Bibliographic Details
Main Authors: Hanaa Hardi, Rahma Melki, Zouhour Boughaleb, Tijani El Harroudi, Souria Aissaoui, Noureddine Boukhatem
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Cancer
Subjects:
Breast cancer
ERCC2
MTHFR
Genetics
Single nucleotide polymorphism
Haplotype
Online Access:http://link.springer.com/article/10.1186/s12885-018-4214-z

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