Tunable activation of therapeutic platelet-rich plasma by pulse electric field: Differential effects on clot formation, growth factor release, and platelet morphology.

Tunable activation of therapeutic platelet-rich plasma by pulse electric field: Differential effects on clot formation, growth factor release, and platelet morphology.

BACKGROUND:Activation of platelet-rich plasma (PRP) by pulse electric field (PEF) releases growth factors which promote wound healing (e.g., PDGF, VEGF for granulation, EGF for epithelialization). AIMS:To determine after PEF activation of therapeutic PRP: 1) platelet gel strength; 2) profile of rele...

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Bibliographic Details
Main Authors: Andrew L Frelinger, Anja J Gerrits, V Bogdan Neculaes, Thomas Gremmel, Andrew S Torres, Anthony Caiafa, Sabrina L Carmichael, Alan D Michelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6157860?pdf=render

Internet

http://europepmc.org/articles/PMC6157860?pdf=render

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