Validation of Hepatocellular Carcinoma Experimental Models for TGF-β Promoting Tumor Progression

Validation of Hepatocellular Carcinoma Experimental Models for TGF-β Promoting Tumor Progression

Transforming growth factor beta (TGF-β) is a pleiotropic cytokine with dual role in hepatocellular carcinoma (HCC). It acts as tumor-suppressor and tumor-promoter in the early and late stage respectively. TGF-β influences the tumor-stroma cross-talk affecting the tumoral microenvir...

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Bibliographic Details
Main Authors: Serena Mancarella, Silke Krol, Alberto Crovace, Stefano Leporatti, Francesco Dituri, Martina Frusciante, Gianluigi Giannelli
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
hepatocellular carcinoma
tgf-β
tumor microenvironment
galunisertib
Online Access:https://www.mdpi.com/2072-6694/11/10/1510

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https://www.mdpi.com/2072-6694/11/10/1510

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