Unexpected plasticity in the life cycle of Trypanosoma brucei

Unexpected plasticity in the life cycle of Trypanosoma brucei

African trypanosomes cause sleeping sickness in humans and nagana in cattle. These unicellular parasites are transmitted by the bloodsucking tsetse fly. In the mammalian host’s circulation, proliferating slender stage cells differentiate into cell cycle-arrested stumpy stage cells when they reach hi...

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Bibliographic Details
Main Authors: Sarah Schuster, Jaime Lisack, Ines Subota, Henriette Zimmermann, Christian Reuter, Tobias Mueller, Brooke Morriswood, Markus Engstler
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
trypanosoma
sleeping sickness
tsetse fly
transmission
life cycle
development
Online Access:https://elifesciences.org/articles/66028

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