Polydextrose changes the gut microbiome and attenuates fasting triglyceride and cholesterol levels in Western diet fed mice

Polydextrose changes the gut microbiome and attenuates fasting triglyceride and cholesterol levels in Western diet fed mice

Abstract Obesity and dyslipidemia are hallmarks of metabolic and cardiovascular diseases. Polydextrose (PDX), a soluble fiber has lipid lowering effects. We hypothesize that PDX reduces triglycerides and cholesterol by influencing gut microbiota, which in turn modulate intestinal gene expression. C5...

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Bibliographic Details
Main Authors: Ghulam Shere Raza, Heli Putaala, Ashley A. Hibberd, Esa Alhoniemi, Kirsti Tiihonen, Kari Antero Mäkelä, Karl-Heinz Herzig
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05259-3

Internet

https://doi.org/10.1038/s41598-017-05259-3

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