Chromatin state changes during neural development revealed by in vivo cell-type specific profiling

Chromatin state changes during neural development revealed by in vivo cell-type specific profiling

While transitions between active and repressive chromatin states are essential for differentiation, little is known regarding their role during development of the brain in Drosophila. Here, the authors investigate the large scale chromatin remodelling taking place during fly neural development.

Bibliographic Details
Main Authors: Owen J. Marshall, Andrea H. Brand
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02385-4
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spelling doaj-bc5d1a39368f498dbb4dd3a917d311722021-05-11T07:15:06ZengNature Publishing GroupNature Communications2041-17232017-12-01811910.1038/s41467-017-02385-4Chromatin state changes during neural development revealed by in vivo cell-type specific profilingOwen J. Marshall0Andrea H. Brand1The Gurdon Institute and Department of Physiology, Development and Neuroscience, University of CambridgeThe Gurdon Institute and Department of Physiology, Development and Neuroscience, University of CambridgeWhile transitions between active and repressive chromatin states are essential for differentiation, little is known regarding their role during development of the brain in Drosophila. Here, the authors investigate the large scale chromatin remodelling taking place during fly neural development.https://doi.org/10.1038/s41467-017-02385-4
collection DOAJ
language English
format Article
sources DOAJ
author Owen J. Marshall
Andrea H. Brand
spellingShingle Owen J. Marshall
Andrea H. Brand
Chromatin state changes during neural development revealed by in vivo cell-type specific profiling
Nature Communications
author_facet Owen J. Marshall
Andrea H. Brand
author_sort Owen J. Marshall
title Chromatin state changes during neural development revealed by in vivo cell-type specific profiling
title_short Chromatin state changes during neural development revealed by in vivo cell-type specific profiling
title_full Chromatin state changes during neural development revealed by in vivo cell-type specific profiling
title_fullStr Chromatin state changes during neural development revealed by in vivo cell-type specific profiling
title_full_unstemmed Chromatin state changes during neural development revealed by in vivo cell-type specific profiling
title_sort chromatin state changes during neural development revealed by in vivo cell-type specific profiling
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-12-01
description While transitions between active and repressive chromatin states are essential for differentiation, little is known regarding their role during development of the brain in Drosophila. Here, the authors investigate the large scale chromatin remodelling taking place during fly neural development.
url https://doi.org/10.1038/s41467-017-02385-4
work_keys_str_mv AT owenjmarshall chromatinstatechangesduringneuraldevelopmentrevealedbyinvivocelltypespecificprofiling
AT andreahbrand chromatinstatechangesduringneuraldevelopmentrevealedbyinvivocelltypespecificprofiling
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