Differential effects of accumbens core vs. shell lesions in a rat concurrent conditioned place preference paradigm for cocaine vs. social interaction.

A main challenge in the therapy of drug dependent individuals is to help them reactivate interest in non-drug-associated activities. Among these activities, social interaction is doubly important because treatment adherence itself depends on it. We previously developed a rat experimental model based...

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Bibliographic Details
Main Authors: Michael Fritz, Rana El Rawas, Sabine Klement, Kai Kummer, Michael J Mayr, Vincent Eggart, Ahmad Salti, Michael T Bardo, Alois Saria, Gerald Zernig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3202564?pdf=render