A new understanding of the pathogenesis of nonalcoholic fatty liver disease

A new understanding of the pathogenesis of nonalcoholic fatty liver disease

The incidence rate of nonalcoholic fatty liver disease (NAFLD) has been increasing in China in recent years and has reached 11%-15%. At present, the "multiple-hit" hypothesis is considered the main pathogenesis of NAFLD, yet the specific pathogenesis remains unknown. This article elaborate...

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Main Authors: XIN Shengliang, XU Keshu
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2017-08-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=8400
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spelling doaj-bc28e3ae7bc24b26a6bfd787fb3344ff2020-11-24T21:45:50ZzhoEditorial Department of Journal of Clinical HepatologyLinchuang Gandanbing Zazhi1001-52561001-52562017-08-013381581158310.3969/j.issn.1001-5256.2017.08.037A new understanding of the pathogenesis of nonalcoholic fatty liver diseaseXIN Shengliang0XU Keshu1Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, ChinaDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, ChinaThe incidence rate of nonalcoholic fatty liver disease (NAFLD) has been increasing in China in recent years and has reached 11%-15%. At present, the "multiple-hit" hypothesis is considered the main pathogenesis of NAFLD, yet the specific pathogenesis remains unknown. This article elaborates on the roles of carcinoembryonic antigen-related cell adhesion molecule 1 highly expressed in the liver, vitamin D/vitamin D receptor axis, and psychological factors in the development and progression of NAFLD, in order to provide new directions for the research on the pathogenesis of NAFLD in future.http://www.lcgdbzz.org/qk_content.asp?id=8400
collection DOAJ
language zho
format Article
sources DOAJ
author XIN Shengliang
XU Keshu
spellingShingle XIN Shengliang
XU Keshu
A new understanding of the pathogenesis of nonalcoholic fatty liver disease
Linchuang Gandanbing Zazhi
author_facet XIN Shengliang
XU Keshu
author_sort XIN Shengliang
title A new understanding of the pathogenesis of nonalcoholic fatty liver disease
title_short A new understanding of the pathogenesis of nonalcoholic fatty liver disease
title_full A new understanding of the pathogenesis of nonalcoholic fatty liver disease
title_fullStr A new understanding of the pathogenesis of nonalcoholic fatty liver disease
title_full_unstemmed A new understanding of the pathogenesis of nonalcoholic fatty liver disease
title_sort new understanding of the pathogenesis of nonalcoholic fatty liver disease
publisher Editorial Department of Journal of Clinical Hepatology
series Linchuang Gandanbing Zazhi
issn 1001-5256
1001-5256
publishDate 2017-08-01
description The incidence rate of nonalcoholic fatty liver disease (NAFLD) has been increasing in China in recent years and has reached 11%-15%. At present, the "multiple-hit" hypothesis is considered the main pathogenesis of NAFLD, yet the specific pathogenesis remains unknown. This article elaborates on the roles of carcinoembryonic antigen-related cell adhesion molecule 1 highly expressed in the liver, vitamin D/vitamin D receptor axis, and psychological factors in the development and progression of NAFLD, in order to provide new directions for the research on the pathogenesis of NAFLD in future.
url http://www.lcgdbzz.org/qk_content.asp?id=8400
work_keys_str_mv AT xinshengliang anewunderstandingofthepathogenesisofnonalcoholicfattyliverdisease
AT xukeshu anewunderstandingofthepathogenesisofnonalcoholicfattyliverdisease
AT xinshengliang newunderstandingofthepathogenesisofnonalcoholicfattyliverdisease
AT xukeshu newunderstandingofthepathogenesisofnonalcoholicfattyliverdisease
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