A new understanding of the pathogenesis of nonalcoholic fatty liver disease
The incidence rate of nonalcoholic fatty liver disease (NAFLD) has been increasing in China in recent years and has reached 11%-15%. At present, the "multiple-hit" hypothesis is considered the main pathogenesis of NAFLD, yet the specific pathogenesis remains unknown. This article elaborate...
| Main Authors: | , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Hepatology
2017-08-01
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| Series: | Linchuang Gandanbing Zazhi |
| Online Access: | http://www.lcgdbzz.org/qk_content.asp?id=8400 |
| Summary: | The incidence rate of nonalcoholic fatty liver disease (NAFLD) has been increasing in China in recent years and has reached 11%-15%. At present, the "multiple-hit" hypothesis is considered the main pathogenesis of NAFLD, yet the specific pathogenesis remains unknown. This article elaborates on the roles of carcinoembryonic antigen-related cell adhesion molecule 1 highly expressed in the liver, vitamin D/vitamin D receptor axis, and psychological factors in the development and progression of NAFLD, in order to provide new directions for the research on the pathogenesis of NAFLD in future. |
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| ISSN: | 1001-5256 1001-5256 |