Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines.

Combined bezafibrate (BEZ) and medroxyprogesterone acetate (MPA) exert unexpected antileukaemic activities against acute myeloid leukaemia (AML) and these activities are associated with the generation of reactive oxygen species (ROS) within the tumor cells. Although the generation of ROS by these dr...

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Bibliographic Details
Main Authors: Stefano Tiziani, Alessia Lodi, Farhat L Khanim, Mark R Viant, Christopher M Bunce, Ulrich L Günther
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2621336?pdf=render