Nitric oxide synthase dysfunction contributes to impaired cerebroarteriolar reactivity in experimental cerebral malaria.

Nitric oxide synthase dysfunction contributes to impaired cerebroarteriolar reactivity in experimental cerebral malaria.

Cerebrovascular dysfunction plays a key role in the pathogenesis of cerebral malaria. In experimental cerebral malaria (ECM) induced by Plasmodium berghei ANKA, cerebrovascular dysfunction characterized by vascular constriction, occlusion and damage results in impaired perfusion and reduced cerebral...

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Bibliographic Details
Main Authors: Peng Kai Ong, Benoît Melchior, Yuri C Martins, Anthony Hofer, Pamela Orjuela-Sánchez, Pedro Cabrales, Graziela M Zanini, John A Frangos, Leonardo J M Carvalho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23818850/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23818850/?tool=EBI

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