The Highly Expressed FAM83F Protein in Papillary Thyroid Cancer Exerts a Pro-Oncogenic Role in Thyroid Follicular Cells

The Highly Expressed FAM83F Protein in Papillary Thyroid Cancer Exerts a Pro-Oncogenic Role in Thyroid Follicular Cells

Thyroid cancer is the most common endocrine cancer with predominant prevalence of papillary thyroid cancer (PTC) histotype. MAPK signaling genetic alterations are frequent in PTC, affecting more than 80% of cases. These alterations constitutively activate MAPK signaling cross-regulating different pr...

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Bibliographic Details
Main Authors: Cesar Seigi Fuziwara, Kelly Cristina Saito, Suzana Garcia Leoni, Ângela Flávia Logullo Waitzberg, Edna Teruko Kimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Endocrinology
Subjects:
FAM83F
papillary thyroid cancer
thyroid cell differentiation
MAPK signaling
stem-cell genes
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00134/full

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