A heuristic model for computational prediction of human branch point sequence

A heuristic model for computational prediction of human branch point sequence

Abstract Background Pre-mRNA splicing is the removal of introns from precursor mRNAs (pre-mRNAs) and the concurrent ligation of the flanking exons to generate mature mRNA. This process is catalyzed by the spliceosome, where the splicing factor 1 (SF1) specifically recognizes the seven-nucleotide bra...

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Bibliographic Details
Main Authors: Jia Wen, Jue Wang, Qing Zhang, Dianjing Guo
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Bioinformatics
Subjects:
Heuristic model
Bps
Pre-mRNA splicing
Binding energy
Genome-wide prediction
Online Access:http://link.springer.com/article/10.1186/s12859-017-1864-9

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