Programming of neurotoxic cofactor CXCL-10 in HIV-1-associated dementia: abrogation of CXCL-10-induced neuro-glial toxicity in vitro by PKC activator

Programming of neurotoxic cofactor CXCL-10 in HIV-1-associated dementia: abrogation of CXCL-10-induced neuro-glial toxicity in vitro by PKC activator

<p>Abstract</p> <p>Background</p> <p>More than 50% of patients undergoing lifelong suppressive antiviral treatment for HIV-1 infection develop minor HIV-1-associated neurocognitive disorders. Neurological complications during HIV-1 infection are the result of direct neu...

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Bibliographic Details
Main Authors: Mehla Rajeev, Bivalkar-Mehla Shalmali, Nagarkatti Mitzi, Chauhan Ashok
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Journal of Neuroinflammation
Subjects:
TNF-α
CXCR4/CXCR3
Cytokines
Chemokines
Chemotaxis
Bryostatin
Online Access:http://www.jneuroinflammation.com/content/9/1/239

Internet

http://www.jneuroinflammation.com/content/9/1/239

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