Soybean-Derived Phytoalexins Improve Cognitive Function through Activation of Nrf2/HO-1 Signaling Pathway

Soybean-Derived Phytoalexins Improve Cognitive Function through Activation of Nrf2/HO-1 Signaling Pathway

As soy-derived glyceollins are known to induce antioxidant enzymes in various types of cells and tissues, we hypothesized that the compounds could protect neurons from damage due to reactive oxygen species (ROS). In order to examine the neuroprotective effect of glyceollins, primary cortical neurons...

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Bibliographic Details
Main Authors: Ji Yeon Seo, Bo Ram Kim, Jisun Oh, Jong-Sang Kim
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
soybean
phytoalexins
glyceollins
neuroprotection
MAPK
Nrf2
HO-1
Online Access:http://www.mdpi.com/1422-0067/19/1/268

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