Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a.

Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a.

BACKGROUND/AIM:Diabetes-associated myocardial dysfunction results in altered gene expression in the heart. We aimed to investigate the changes in gene expression profiles accompanying diabetes-induced cardiomyopathy and its phenotypic rescue by restoration of SERCA2a expression. METHODS/RESULTS:Usin...

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Bibliographic Details
Main Authors: Ioannis Karakikes, Maengjo Kim, Lahouaria Hadri, Susumu Sakata, Yezhou Sun, Weijia Zhang, Elie R Chemaly, Roger J Hajjar, Djamel Lebeche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2714457?pdf=render

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