Identification of an intrinsic determinant critical for maspin subcellular localization and function.

Identification of an intrinsic determinant critical for maspin subcellular localization and function.

Maspin, a multifaceted tumor suppressor, belongs to the serine protease inhibitor superfamily, but only inhibits serine protease-like enzymes such as histone deacetylase 1 (HDAC1). Maspin is specifically expressed in epithelial cells and it is differentially regulated during tumor progression. A new...

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Main Authors: Sijana H Dzinic, Alexander Kaplun, Xiaohua Li, Margarida Bernardo, Yonghong Meng, Ivory Dean, David Krass, Paul Stemmer, Namhee Shin, Fulvio Lonardo, Shijie Sheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3837015?pdf=render

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