Characterization of a NDM-1- Encoding Plasmid pHFK418-NDM From a Clinical Proteus mirabilis Isolate Harboring Two Novel Transposons, Tn6624 and Tn6625

Characterization of a NDM-1- Encoding Plasmid pHFK418-NDM From a Clinical Proteus mirabilis Isolate Harboring Two Novel Transposons, Tn6624 and Tn6625

Acquisition of the blaNDM–1 gene by Proteus mirabilis is a concern because it already has intrinsic resistance to polymyxin E and tigecycline antibiotics. Here, we describe a P. mirabilis isolate that carries a pPrY2001-like plasmid (pHFK418-NDM) containing a blaNDM–1 gene. The pPrY2001-like plasmid...

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Bibliographic Details
Main Authors: Dandan Dong, Manli Li, Zhenzhen Liu, Jiantao Feng, Nan Jia, Hui Zhao, Baohua Zhao, Tingting Zhou, Xianglilan Zhang, Yigang Tong, Yuanqi Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
Proteus mirabilis
blaNDM–1
transposons
plasmids
multidrug-resistant
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02030/full

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