Loss of the <it>Drosophila </it>cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling
<p>Abstract</p> <p>Background</p> <p>Epithelial neoplasias are associated with alterations in cell polarity and excessive cell proliferation, yet how these neoplastic properties are related to one another is still poorly understood. The study of <it>Drosophila <...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-09-01
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| Series: | BMC Developmental Biology |
| Online Access: | http://www.biomedcentral.com/1471-213X/11/57 |