Strain profiling and epidemiology of bacterial species from metagenomic sequencing

Strain profiling and epidemiology of bacterial species from metagenomic sequencing

Microbiota is often a complex mixture of multiple coexisting species and strains with high level of phenotypic and genomic variability. Here, Albanese and Donati develop StrainEst for estimating the number and identity of coexisting strains and their relative abundances in mixed metagenomic samples.

Bibliographic Details
Main Authors: Davide Albanese, Claudio Donati
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02209-5
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spelling doaj-bbdd0bfb3791437cb7966ed2a7f182722021-05-11T07:21:59ZengNature Publishing GroupNature Communications2041-17232017-12-018111410.1038/s41467-017-02209-5Strain profiling and epidemiology of bacterial species from metagenomic sequencingDavide Albanese0Claudio Donati1Computational Biology Unit, Research and Innovation Centre, Fondazione Edmund Mach, Via Edmund Mach 1Computational Biology Unit, Research and Innovation Centre, Fondazione Edmund Mach, Via Edmund Mach 1Microbiota is often a complex mixture of multiple coexisting species and strains with high level of phenotypic and genomic variability. Here, Albanese and Donati develop StrainEst for estimating the number and identity of coexisting strains and their relative abundances in mixed metagenomic samples.https://doi.org/10.1038/s41467-017-02209-5
collection DOAJ
language English
format Article
sources DOAJ
author Davide Albanese
Claudio Donati
spellingShingle Davide Albanese
Claudio Donati
Strain profiling and epidemiology of bacterial species from metagenomic sequencing
Nature Communications
author_facet Davide Albanese
Claudio Donati
author_sort Davide Albanese
title Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_short Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_full Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_fullStr Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_full_unstemmed Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_sort strain profiling and epidemiology of bacterial species from metagenomic sequencing
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-12-01
description Microbiota is often a complex mixture of multiple coexisting species and strains with high level of phenotypic and genomic variability. Here, Albanese and Donati develop StrainEst for estimating the number and identity of coexisting strains and their relative abundances in mixed metagenomic samples.
url https://doi.org/10.1038/s41467-017-02209-5
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AT claudiodonati strainprofilingandepidemiologyofbacterialspeciesfrommetagenomicsequencing
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