Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells

Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells

The mechanisms underlying the positioning of eukaryotic organelles remain elusive. Here Lin et al. use imaging and a mathematical model to show that microtubule-based transport and active diffusion and actin-based polar drift act together to facilitate even distribution of peroxisomes in filamentous...

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Bibliographic Details
Main Authors: Congping Lin, Martin Schuster, Sofia Cunha Guimaraes, Peter Ashwin, Michael Schrader, Jeremy Metz, Christian Hacker, Sarah Jane Gurr, Gero Steinberg
Format: Article
Language:English
Published: Nature Publishing Group 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11814
Description
Summary:The mechanisms underlying the positioning of eukaryotic organelles remain elusive. Here Lin et al. use imaging and a mathematical model to show that microtubule-based transport and active diffusion and actin-based polar drift act together to facilitate even distribution of peroxisomes in filamentous fungi.
ISSN:2041-1723

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