Altered expression of insulin receptor isoforms in breast cancer.

Altered expression of insulin receptor isoforms in breast cancer.

PURPOSE: Insulin-like growth factor (IGF) signaling through human insulin receptor isoform A (IR-A) contributes to tumorigenesis and intrinsic resistance to anti-IGF1R therapy. In the present study, we (a) developed quantitative TaqMan real time-PCR-based assays (qRT-PCR) to measure human insulin re...

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Bibliographic Details
Main Authors: Jiaqi Huang, Chris Morehouse, Katie Streicher, Brandon W Higgs, Jin Gao, Meggan Czapiga, Anmarie Boutrin, Wei Zhu, Philip Brohawn, Yong Chang, Jaye Viner, Theresa LaVallee, Laura Richman, Bahija Jallal, Yihong Yao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3202518?pdf=render

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