Research advances in non-invasive diagnosis models for liver fibrosis in chronic hepatitis B

It is vital for reducing the occurrence of complications, such as liver cirrhosis and hepatic carcinoma, to early diagnose liver fibrosis in chronic hepatitis B and intervene in time with antiviral therapy. Although liver biopsy is the "golden standard" for the diagnosis of fibrosis, it ha...

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Bibliographic Details
Main Authors: TANG Qingrong, HE Qing, TANG Qiyuan
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2015-08-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=6802
Description
Summary:It is vital for reducing the occurrence of complications, such as liver cirrhosis and hepatic carcinoma, to early diagnose liver fibrosis in chronic hepatitis B and intervene in time with antiviral therapy. Although liver biopsy is the "golden standard" for the diagnosis of fibrosis, it has certain disadvantages, such as complicated operation, invasion, and occurrence of complications. Therefore, non-invasive diagnosis models have gained more and more attention clinically. In this review, we summarizes the non-invasive diagnosis models for chronic hepatitis B that have been established throughout the world. It is noticed that there are a number of models being studied and each model has a diagnostic value, to some degree, but a lack of consensus exists. The development of more efficient models that can replace liver biopsy still needs further research to assess liver fibrosis in chronic hepatitis B and guide antiviral therapy.
ISSN:1001-5256
1001-5256