Tertiary lymphoid structure related B-cell IgE isotype switching and secondary lymphoid organ linked IgE production in mouse allergy model

Tertiary lymphoid structure related B-cell IgE isotype switching and secondary lymphoid organ linked IgE production in mouse allergy model

Abstract Background Numerous data obtained by different research laboratories indicate that specific IgE production is triggered independently of specific IgG or IgA ones and so it is not linked to fully matured germinal centers formation in the secondary lymphoid organs. The aim of this study was t...

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Bibliographic Details
Main Authors: Dmitrii Borisovich Chudakov, Dmitrii Yuryevich Ryasantsev, Daria Sergeevna Tsaregorotseva, Olga Dmitrievna Kotsareva, Gulnar Vaisovna Fattakhova, Elena Viktorovna Svirshchevskaya
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Immunology
Subjects:
IgE-mediated allergy
Tertiary lymphoid structures
Low allergen doses
Anti-proliferative drugs
Local IgE class switching
Online Access:http://link.springer.com/article/10.1186/s12865-020-00376-7

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