Regulation of hepatocyte growth factor in mice with pneumonia by peptidases and trans-alveolar flux.

Regulation of hepatocyte growth factor in mice with pneumonia by peptidases and trans-alveolar flux.

Hepatocyte growth factor (HGF) promotes lung epithelial repair after injury. Because prior studies established that human neutrophil proteases inactivate HGF in vitro, we predicted that HGF levels decrease in lungs infiltrated with neutrophils and that injury is less severe in lungs lacking HGF-inac...

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Bibliographic Details
Main Authors: Wilfred W Raymond, Xiang Xu, Shilpa Nimishakavi, Catherine Le, Donald M McDonald, George H Caughey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4418689?pdf=render

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