Role of Polymeric Excipients in the Stabilization of Olanzapine when Exposed to Aqueous Environments

Hydrate formation is a phase transition which can occur during manufacturing processes involving water. This work considers the prevention of hydration of anhydrous olanzapine and hydrate conversions in the presence of water and polymers (polyethyleneglycol; hydroxypropylcellulose; polyvinylpyrrolid...

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Bibliographic Details
Main Authors: Maria Paisana, Martin Wahl, João Pinto
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/12/19832