Overexpression of p67phox in Response to Fluoropyrimidines in HCT116 Cells

Objectives: Cancer cells require reactive oxygen species (ROS) in order to keep up with growth rate. The accumulation of ROS induced by anticancer drugs can promote cell death through oxidative damage. A potential source of ROS is the family of NADPH oxidase (NOX) enzyme that produces ROS as thei...

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Bibliographic Details
Main Authors: Ufuk Ozer, Karen Wood Barbour
Format: Article
Language:English
Published: Dicle University Medical School 2016-12-01
Series:Dicle Medical Journal
Subjects:
ROS
Online Access:http://www.diclemedj.org/upload/sayi/62/Dicle%20Med%20J-03067.pdf