Risk factors influencing prognosis in surgical patients with proliferative diabetic retinopathy

• Main Authors: Chao-Lan Shen, Kong-Qian Huang, Ling Cui, Ming-Liang Lyu, Fen Tang, Hai-Bin Zhong, Xin Zhao
• Format: Article
• Language: English
• Published: Press of International Journal of Ophthalmology (IJO PRESS) 2020-04-01
• Series: Guoji Yanke Zazhi
• Subjects: oct; proliferative diabetic retinopathy; hemoglobin a1c; prognosis; risk factor
• Online Access: http://ies.ijo.cn/cn_publish/2020/4/202004028.pdf
• ISSN: 1672-5123; 1672-5123

AIM: To investigate the clinical and imaging data of proliferative diabetic retinopathy(PDR)treated by pars plana vitrectomy(PPV), and to further explore the risk factors associated with poor prognosis. <p>METHODS: Data of 90 eyes of 90 patients at Guangxi Zhuang Autonomous Region People's Hospital from January 2016 to December 2018 were retrospectively reviewed. According to the postoperative visual acuity, the patients were divided into favorable prognosis group(group A)and unfavorable prognosis group(group B). To explore the clinical and image risk factors and prognosis of disease outcome. Univariate analysis uses Chi-square analysis,while multivariate analysis takes Logistic regression analysis. <p>RESULTS: Univariate analysis showed that there was much more difference between good prognosis and those with poor prognosis: the preoperational PRP treatment experience(<i>P</i>=0.042), HbA1c(<i>P</i>=0.008), OCT-TRD(<i>P</i>=0.004), OCT-HRF(<i>P</i>=0.005). Multivariate logistic regression analysis showed that HbA1c(<i>OR</i>=1.439, <i>P</i>=0.009)and OCT-TRD(<i>OR</i>=4.007, <i>P</i>=0.040)were independent risk factors for poor prognosis after proliferative diabetic retinopathy. <p>CONCLUSION: HbA1c and OCT-TRD are independent predictors of poor prognosis in PDR patient.