Biochemical and biophysical characterization of the deadenylase CrCaf1 from Chlamydomonas reinhardtii.

The modulation of mRNA turnover has been increasingly recognized as a hotpoint for gene expression regulation at the post-transcriptional level. In eukaryotic cells, most mRNAs are degraded via the deadenylation-dependent pathway, in which the removal of the poly(A) tail is the initial and rate-limi...

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Bibliographic Details
Main Authors: Jia-Quan Zhang, Guang-Jun He, Yong-Bin Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720613?pdf=render