Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells

Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells

Epigenetic regulation serves as the basis for stem cell differentiation into distinct cell types, but it is unclear how global epigenetic changes are regulated during this process. Here, we tested the hypothesis that global chromatin organization affects the lineage potential of stem cells and that...

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Bibliographic Details
Main Authors: Fernando Ugarte, Rebekah Sousae, Bertrand Cinquin, Eric W. Martin, Jana Krietsch, Gabriela Sanchez, Margaux Inman, Herman Tsang, Matthew Warr, Emmanuelle Passegué, Carolyn A. Larabell, E. Camilla Forsberg
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115002714

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