Deriving a mutation index of carcinogenicity using protein structure and protein interfaces.
With the advent of Next Generation Sequencing the identification of mutations in the genomes of healthy and diseased tissues has become commonplace. While much progress has been made to elucidate the aetiology of disease processes in cancer, the contributions to disease that many individual mutation...
Main Authors: | Octavio Espinosa, Konstantinos Mitsopoulos, Jarle Hakas, Frances Pearl, Marketa Zvelebil |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3893166?pdf=render |
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