PepO is a target of the two-component systems VicRK and CovR required for systemic virulence of Streptococcus mutans

PepO is a target of the two-component systems VicRK and CovR required for systemic virulence of Streptococcus mutans

Streptococcus mutans , a cariogenic species, is often associated with cardiovascular infections. Systemic virulence of specific S. mutans serotypes has been associated with the expression of the collagen- and laminin-binding protein Cnm, which is transcriptionally regulated by VicRK and CovR. In thi...

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Bibliographic Details
Main Authors: Lívia A. Alves, Tridib Ganguly, Érika N. Harth-Chú, Jessica Kajfasz, José A. Lemos, Jacqueline Abranches, Renata O. Mattos-Graner
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Virulence
Subjects:
streptococcus mutans
systemic infections
two component system
peptidases
complement system
cardiovascular diseases
Online Access:http://dx.doi.org/10.1080/21505594.2020.1767377

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