Multi-criteria optimization of regulation in metabolic networks.

Determining the regulation of metabolic networks at genome scale is a hard task. It has been hypothesized that biochemical pathways and metabolic networks might have undergone an evolutionary process of optimization with respect to several criteria over time. In this contribution, a multi-criteria a...

Full description

Bibliographic Details
Main Authors: Clara Higuera, Alejandro F Villaverde, Julio R Banga, John Ross, Federico Morán
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3406099?pdf=render