Bitter Taste Receptor T2R14 Modulates Gram-Positive Bacterial Internalization and Survival in Gingival Epithelial Cells

Bitter Taste Receptor T2R14 Modulates Gram-Positive Bacterial Internalization and Survival in Gingival Epithelial Cells

Bitter-taste receptors (T2Rs) have emerged as key players in host–pathogen interactions and important modulators of oral innate immunity. Previously, we reported that T2R14 is expressed in gingival epithelial cells (GECs) and interacts with competence stimulating peptides (CSPs) secreted by the cari...

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Bibliographic Details
Main Authors: Manoj Reddy Medapati, Anjali Yadav Bhagirath, Nisha Singh, Robert J. Schroth, Rajinder P. Bhullar, Kangmin Duan, Prashen Chelikani
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
gingival epithelial cell
G-protein-coupled receptor (GPCR)
Gram-positive bacteria
host-microbe interaction
innate immunity
internalization
Online Access:https://www.mdpi.com/1422-0067/22/18/9920

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https://www.mdpi.com/1422-0067/22/18/9920

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