Neoplasia from Genetic Point of View

Cancer is a genetic-epigenetic based disease which contains a complex of alterations that cause irreversible transformation of cells with a new anarchic behavior. Tumor suppressor inactivation and/or oncogene activation will lead to tumorigenesis. Based on the genetic alteration in germ or somatic...

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Main Authors:	Reza Shirkoohi, Cyrus Azimi
Format:	Article
Language:	English
Published:	Tehran University of Medical Sciences 2013-10-01
Series:	Acta Medica Iranica
Subjects:	Cancer Cytogenetics Epigenetics Genetics Oncogenes Tumor suppressors
Online Access:	https://acta.tums.ac.ir/index.php/acta/article/view/4385

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spelling	doaj-bb667faea6f741988d4f52fc61d1c1cc2020-11-25T02:52:02ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942013-10-0151104338Neoplasia from Genetic Point of ViewReza Shirkoohi0Cyrus Azimi1Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran. Cancer is a genetic-epigenetic based disease which contains a complex of alterations that cause irreversible transformation of cells with a new anarchic behavior. Tumor suppressor inactivation and/or oncogene activation will lead to tumorigenesis. Based on the genetic alteration in germ or somatic cells, the affected person will have a different fate of cancer incidence or inheritable cancer susceptibility syndrome. Knowing the mechanism of molecular and cytogenetic alterations in cancer will give an advantage in finding more practical approaches to cancer management. In this review, the cancer genetics is discussed from different aspects. https://acta.tums.ac.ir/index.php/acta/article/view/4385CancerCytogeneticsEpigeneticsGeneticsOncogenesTumor suppressors
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Reza Shirkoohi Cyrus Azimi
spellingShingle	Reza Shirkoohi Cyrus Azimi Neoplasia from Genetic Point of View Acta Medica Iranica Cancer Cytogenetics Epigenetics Genetics Oncogenes Tumor suppressors
author_facet	Reza Shirkoohi Cyrus Azimi
author_sort	Reza Shirkoohi
title	Neoplasia from Genetic Point of View
title_short	Neoplasia from Genetic Point of View
title_full	Neoplasia from Genetic Point of View
title_fullStr	Neoplasia from Genetic Point of View
title_full_unstemmed	Neoplasia from Genetic Point of View
title_sort	neoplasia from genetic point of view
publisher	Tehran University of Medical Sciences
series	Acta Medica Iranica
issn	0044-6025 1735-9694
publishDate	2013-10-01
description	Cancer is a genetic-epigenetic based disease which contains a complex of alterations that cause irreversible transformation of cells with a new anarchic behavior. Tumor suppressor inactivation and/or oncogene activation will lead to tumorigenesis. Based on the genetic alteration in germ or somatic cells, the affected person will have a different fate of cancer incidence or inheritable cancer susceptibility syndrome. Knowing the mechanism of molecular and cytogenetic alterations in cancer will give an advantage in finding more practical approaches to cancer management. In this review, the cancer genetics is discussed from different aspects.
topic	Cancer Cytogenetics Epigenetics Genetics Oncogenes Tumor suppressors
url	https://acta.tums.ac.ir/index.php/acta/article/view/4385
work_keys_str_mv	AT rezashirkoohi neoplasiafromgeneticpointofview AT cyrusazimi neoplasiafromgeneticpointofview
_version_	1724731801124995072

Neoplasia from Genetic Point of View

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