Existence of periodic solutions in the modified Wheldon model of CML
The Wheldon model (1975) of a chronic myelogenous leukemia (CML) dynamics is modified and enriched by introduction of a time-varying microenvironment and time-dependent drug efficacies. The resulting model is a special class of nonautonomous nonlinear system of differential equations with delays...
Main Authors: | Pablo Amster, Rocio Balderrama, Lev Idels |
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Format: | Article |
Language: | English |
Published: |
Texas State University
2013-12-01
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Series: | Electronic Journal of Differential Equations |
Subjects: | |
Online Access: | http://ejde.math.txstate.edu/Volumes/2013/272/abstr.html |
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