Brain-derived neurotrophic factor promotes human granulosa-like tumor cell steroidogenesis and proliferation by activating the FSH receptor-mediated signaling pathway

Brain-derived neurotrophic factor promotes human granulosa-like tumor cell steroidogenesis and proliferation by activating the FSH receptor-mediated signaling pathway

Abstract Brain-derived neurotrophic factor (BDNF) and FSH receptor (FSHR) are expressed in ovarian granulosa cells, and play important roles in regulating follicle growth and oocyte maturation. Studies have linked the BDNF-associated signaling pathway to FSHR mRNA expression in the regulation of fol...

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Bibliographic Details
Main Authors:	Min Xie, Meiling Li, Ji Zhou, Xiaomeng Ding, Yidan Shao, Jun Jing, Yuxiu Liu, Bing Yao
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-03-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-017-00203-x

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